

All basic cassettes (CreIRESmCherry, ROSA targeting vector, etc) are complete.

Initial plan is to make four BAC transgenics (Krt6-Cre, Tbx22-CreERT2, dNp63-CreERT2, Lhx7/8-Cre) and three enhancer (Visel project) CreERT2 lines (R26 knock-in).Goal: To generate 15 Cre driver strains for orofacialclefting research.new ENU induced mutant strain (on FVB.A) įaceBaseCre Driver Project:Current progress and future plans.Bambi, Osr1, Osr2, Jag2, Snai1 and Snai2, Gad1, Slc32a1, Tgfbr2, Wnt9b.new knockout strains - most on B6 129 background.most are public, some still private, some imported and under development for distribution.~ 50 strains in the JAX FaceBase Repository.The Jackson LaboratoryBar Harbor, MEįaceBase Mouse Repository at JAX importation, cryopreservation, GQC, distribution Genetic tools and resources for orofacialclefting research PIs: Leah Rae Donahue, Ph.D.
